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Crystal Structures of Tubulin Acetyltransferase Reveal a Conserved Catalytic Core and the Plasticity of the Essential N Terminus

Tubulin acetyltransferase (TAT) acetylates Lys-40 of α-tubulin in the microtubule lumen. TAT is inefficient, and its activity is enhanced when tubulin is incorporated in microtubules. Acetylation is associated with stable microtubules and regulates the binding of microtubule motors and associated pr...

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Bibliografiske detaljer
Main Authors: Kormendi, Vasilisa, Szyk, Agnieszka, Piszczek, Grzegorz, Roll-Mecak, Antonina
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516708/
https://ncbi.nlm.nih.gov/pubmed/23105108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.421222
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