Crystal Structures of Tubulin Acetyltransferase Reveal a Conserved Catalytic Core and the Plasticity of the Essential N Terminus

Tubulin acetyltransferase (TAT) acetylates Lys-40 of α-tubulin in the microtubule lumen. TAT is inefficient, and its activity is enhanced when tubulin is incorporated in microtubules. Acetylation is associated with stable microtubules and regulates the binding of microtubule motors and associated pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kormendi, Vasilisa, Szyk, Agnieszka, Piszczek, Grzegorz, Roll-Mecak, Antonina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516708/
https://ncbi.nlm.nih.gov/pubmed/23105108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.421222
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