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Katanin spiral and ring structures shed light on power stroke for microtubule severing

Microtubule-severing enzymes katanin, spastin and fidgetin are AAA ATPases important for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. Because of a lack of 3D structures, their mechanism has remained poorly understood. Here we report the first X-ray struc...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Zehr, Elena, Szyk, Agnieszka, Piszczek, Grzegorz, Szczesna, Ewa, Zuo, Xiaobing, Roll-Mecak, Antonina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152510/
https://ncbi.nlm.nih.gov/pubmed/28783150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3448
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