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Katanin spiral and ring structures shed light on power stroke for microtubule severing
Microtubule-severing enzymes katanin, spastin and fidgetin are AAA ATPases important for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. Because of a lack of 3D structures, their mechanism has remained poorly understood. Here we report the first X-ray struc...
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| Publicado en: | Nat Struct Mol Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7152510/ https://ncbi.nlm.nih.gov/pubmed/28783150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3448 |
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