Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase

Acetylation of α-tubulin Lys40 by tubulin acetyltransferase (TAT) is the only known posttranslational modification in the microtubule lumen. It marks stable microtubules and is required for polarity establishment and directional migration. Here we elucidate the mechanistic underpinnings for TAT acti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Szyk, Agnieszka, Deaconescu, Alexandra M., Spector, Jeffrey, Goodman, Benjamin, Valenstein, Max L., Ziolkowska, Natasza E., Kormendi, Vasilisa, Grigorieff, Nikolaus, Roll-Mecak, Antonina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726456/
https://ncbi.nlm.nih.gov/pubmed/24906155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.061
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