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Crystal Structures of Tubulin Acetyltransferase Reveal a Conserved Catalytic Core and the Plasticity of the Essential N Terminus

Tubulin acetyltransferase (TAT) acetylates Lys-40 of α-tubulin in the microtubule lumen. TAT is inefficient, and its activity is enhanced when tubulin is incorporated in microtubules. Acetylation is associated with stable microtubules and regulates the binding of microtubule motors and associated pr...

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מידע ביבליוגרפי
Main Authors: Kormendi, Vasilisa, Szyk, Agnieszka, Piszczek, Grzegorz, Roll-Mecak, Antonina
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516708/
https://ncbi.nlm.nih.gov/pubmed/23105108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.421222
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