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Spectroscopic and DFT Studies of Second Sphere Variants of the Type 1 Copper Site in Azurin: Covalent and Non-Local Electrostatic Contributions to Reduction Potentials

The reduction potentials (E(0)) of type 1 (T1) or blue copper (BC) sites in proteins and enzymes with identical first coordination spheres around the redox active copper ion can vary by ~400 mV. Here, we use a combination of low temperature electronic absorption and magnetic circular dichroism, elec...

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Detalhes bibliográficos
Main Authors: Hadt, Ryan G., Sun, Ning, Marshall, Nicholas M., Hodgson, Keith O., Hedman, Britt, Lu, Yi, Solomon, Edward I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506006/
https://ncbi.nlm.nih.gov/pubmed/22985400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja306438n
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