Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation–π interactions

Alkyltransferase-like (ATL) proteins in Schizosaccharomyces pombe (Atl1) and Thermus thermophilus (TTHA1564) protect against the adverse effects of DNA alkylation damage by flagging O(6)-alkylguanine lesions for nucleotide excision repair (NER). We show that both ATL proteins bind with high affinity...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wilkinson, Oliver J., Latypov, Vitaly, Tubbs, Julie L., Millington, Christopher L., Morita, Rihito, Blackburn, Hannah, Marriott, Andrew, McGown, Gail, Thorncroft, Mary, Watson, Amanda J., Connolly, Bernard A., Grasby, Jane A., Masui, Ryoji, Hunter, Christopher A., Tainer, John A., Margison, Geoffrey P., Williams, David M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503161/
https://ncbi.nlm.nih.gov/pubmed/23112169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209451109
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