Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines

Nucleotide excision repair (NER) has long been known to remove DNA lesions induced by chemical carcinogens, and the molecular mechanism has been partially elucidated. Here we demonstrate that in S.pombe a DNA recognition protein, alkyltransferase-like 1 (Atl1), can play a pivotal role in selecting a...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Latypov, Vitaly F., Tubbs, Julie L., Watson, Amanda J., Marriott, Andrew S., McGown, Gail, Thorncroft, Mary, Wilkinson, Oliver J., Senthong, Pattama, Butt, Amna, Arvai, Andrew S., Millington, Christopher L., Povey, Andrew C., Williams, David M., Santibanez-Koref, Mauro F., Tainer, John A., Margison, Geoffrey P.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2012
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398191/
https://ncbi.nlm.nih.gov/pubmed/22658721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.04.028
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