Loading...

The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II

Dovitinib (TKI258/CHIR258) is a multi-kinase inhibitor in phase III development for the treatment of several cancers. Dovitinib is a benzimidazole-quinolinone compound that structurally resembles the bisbenzimidazole minor groove binding dye Hoechst 33258. Dovitinib bound to DNA as shown by its abil...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hasinoff, Brian B., Wu, Xing, Nitiss, John L., Kanagasabai, Ragu, Yalowich, Jack C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501595/
https://ncbi.nlm.nih.gov/pubmed/23041231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.09.023
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!