Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN-γ-Mediated Inhibition of Norovirus Replication in Macrophages

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transcription facto...

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Autors principals: Maloney, Nicole S., Thackray, Larissa B., Goel, Gautam, Hwang, Seungmin, Duan, Erning, Vachharajani, Punit, Xavier, Ramnik, Virgin, Herbert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Cellular Response to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497668/
https://ncbi.nlm.nih.gov/pubmed/22973039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-12
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