Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN-γ-Mediated Inhibition of Norovirus Replication in Macrophages

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transcription facto...

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Main Authors: Maloney, Nicole S., Thackray, Larissa B., Goel, Gautam, Hwang, Seungmin, Duan, Erning, Vachharajani, Punit, Xavier, Ramnik, Virgin, Herbert W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
Cellular Response to Infection
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497668/
https://ncbi.nlm.nih.gov/pubmed/22973039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-12
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