Critical Role for Interferon Regulatory Factor 3 (IRF-3) and IRF-7 in Type I Interferon-Mediated Control of Murine Norovirus Replication

Human noroviruses (HuNoV) are the major cause of epidemic, nonbacterial gastroenteritis in the world. The short course of HuNoV-induced symptoms has implicated innate immunity in control of norovirus (NoV) infection. Studies using murine norovirus (MNV) confirm the importance of innate immune respon...

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Detalhes bibliográficos
Main Authors: Thackray, Larissa B., Duan, Erning, Lazear, Helen M., Kambal, Amal, Schreiber, Robert D., Diamond, Michael S., Virgin, Herbert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503103/
https://ncbi.nlm.nih.gov/pubmed/23035219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01824-12
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