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Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN-γ-Mediated Inhibition of Norovirus Replication in Macrophages

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transcription facto...

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Hlavní autoři: Maloney, Nicole S., Thackray, Larissa B., Goel, Gautam, Hwang, Seungmin, Duan, Erning, Vachharajani, Punit, Xavier, Ramnik, Virgin, Herbert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497668/
https://ncbi.nlm.nih.gov/pubmed/22973039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-12
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