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Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

Host resistance to viral infection requires type I (α/β) and II (γ) interferon (IFN) production. Another important defense mechanism is the degradative activity of macroautophagy (herein autophagy), mediated by the coordinated action of evolutionarily conserved autophagy proteins (Atg). We show that...

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Bibliografische gegevens
Hoofdauteurs: Hwang, Seungmin, Maloney, Nicole S., Bruinsma, Monique W., Goel, Gautam, Duan, Erning, Zhang, Lei, Shrestha, Bimmi, Diamond, Michael S., Dani, Adish, Sosnovtsev, Stanislav V., Green, Kim Y., Lopez-Otin, Carlos, Xavier, Ramnik J., Thackray, Larissa B., Virgin, Herbert W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Inc. 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348177/
https://ncbi.nlm.nih.gov/pubmed/22520467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.03.002
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