Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

Host resistance to viral infection requires type I (α/β) and II (γ) interferon (IFN) production. Another important defense mechanism is the degradative activity of macroautophagy (herein autophagy), mediated by the coordinated action of evolutionarily conserved autophagy proteins (Atg). We show that...

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Détails bibliographiques
Auteurs principaux: Hwang, Seungmin, Maloney, Nicole S., Bruinsma, Monique W., Goel, Gautam, Duan, Erning, Zhang, Lei, Shrestha, Bimmi, Diamond, Michael S., Dani, Adish, Sosnovtsev, Stanislav V., Green, Kim Y., Lopez-Otin, Carlos, Xavier, Ramnik J., Thackray, Larissa B., Virgin, Herbert W.
Format: Artigo
Langue:Inglês
Publié: Elsevier Inc. 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348177/
https://ncbi.nlm.nih.gov/pubmed/22520467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.03.002
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