Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

Host resistance to viral infection requires type I (α/β) and II (γ) interferon (IFN) production. Another important defense mechanism is the degradative activity of macroautophagy (herein autophagy), mediated by the coordinated action of evolutionarily conserved autophagy proteins (Atg). We show that...

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Autori principali: Hwang, Seungmin, Maloney, Nicole S., Bruinsma, Monique W., Goel, Gautam, Duan, Erning, Zhang, Lei, Shrestha, Bimmi, Diamond, Michael S., Dani, Adish, Sosnovtsev, Stanislav V., Green, Kim Y., Lopez-Otin, Carlos, Xavier, Ramnik J., Thackray, Larissa B., Virgin, Herbert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348177/
https://ncbi.nlm.nih.gov/pubmed/22520467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.03.002
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