Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN-γ-Mediated Inhibition of Norovirus Replication in Macrophages

Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely understood. Here we report that the transcription facto...

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Bibliographic Details
Main Authors: Maloney, Nicole S., Thackray, Larissa B., Goel, Gautam, Hwang, Seungmin, Duan, Erning, Vachharajani, Punit, Xavier, Ramnik, Virgin, Herbert W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497668/
https://ncbi.nlm.nih.gov/pubmed/22973039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-12
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