Llwytho...

Structures of dNTP Intermediate States During DNA Polymerase Active Site Assembly

DNA polymerase and substrate conformational changes are essential for high fidelity DNA synthesis. Structures of DNA polymerase (pol) β in complex with DNA show the enzyme in an ‘open’ conformation. Subsequent to binding the nucleotide, the polymerase ‘closes’ around the nascent base pair with two m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Freudenthal, Bret D., Beard, William A., Wilson, Samuel H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496073/
https://ncbi.nlm.nih.gov/pubmed/22959623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.008
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