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The control of the discrimination between dNTP and rNTP in DNA and RNA polymerase

Understanding the origin of discrimination between rNTP and dNTP by DNA/RNA polymerases is important both for gaining fundamental knowledge on the corresponding systems and for advancing the design of specific drugs. This work explores the nature of this discrimination by systematic calculations of...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Yoon, Hanwool, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073073/
https://ncbi.nlm.nih.gov/pubmed/27480935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25104
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