Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

Channel activators (potentiators) of cystic fibrosis (CF) transmembrane conductance regulator (CFTR), can be used for the treatment of the small subset of CF patients that carry plasma membrane-resident CFTR mutants. However, approximately 90% of CF patients carry the misfolded ΔF508-CFTR and are po...

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Bibliografiset tiedot
Päätekijät: Luciani, Alessandro, Villella, Valeria Rachela, Esposito, Speranza, Gavina, Manuela, Russo, Ilaria, Silano, Marco, Guido, Stefano, Pettoello-Mantovani, Massimo, Carnuccio, Rosa, Scholte, Bob, De Matteis, Antonella, Maiuri, Maria Chiara, Raia, Valeria, Luini, Alberto, Kroemer, Guido, Maiuri, Luigi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2012
Aiheet:
Translational Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494594/
https://ncbi.nlm.nih.gov/pubmed/22874563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21483
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