Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

Centenarians’ offspring represent a suitable model to study age-dependent variables (e.g. IGF-I) potentially involved in the modulation of the lifespan. The aim of the present study was to investigate the role of the IGF-I in human longevity. We evaluated circulating IGF-I bioactivity measured by an...

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Autori principali: Vitale, Giovanni, Brugts, Michael P, Ogliari, Giulia, Castaldi, Davide, Fatti, Letizia M., Varewijck, Aimee J., Lamberts, Steven W., Monti, Daniela, Bucci, Laura, Cevenini, Elisa, Cavagnini, Francesco, Franceschi, Claudio, Hofland, Leo J, Mari, Daniela, Janssen, Joseph A.M.J.L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2012
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492223/
https://ncbi.nlm.nih.gov/pubmed/22983440
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