Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

Centenarians’ offspring represent a suitable model to study age-dependent variables (e.g. IGF-I) potentially involved in the modulation of the lifespan. The aim of the present study was to investigate the role of the IGF-I in human longevity. We evaluated circulating IGF-I bioactivity measured by an...

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Bibliographic Details
Main Authors: Vitale, Giovanni, Brugts, Michael P, Ogliari, Giulia, Castaldi, Davide, Fatti, Letizia M., Varewijck, Aimee J., Lamberts, Steven W., Monti, Daniela, Bucci, Laura, Cevenini, Elisa, Cavagnini, Francesco, Franceschi, Claudio, Hofland, Leo J, Mari, Daniela, Janssen, Joseph A.M.J.L.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492223/
https://ncbi.nlm.nih.gov/pubmed/22983440
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