IGF-I Bioactivity in an Elderly Population: Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome

OBJECTIVE: There is a complex relationship between IGF-I, IGF binding proteins, growth hormone, and insulin. The IGF-I kinase receptor activation assay (KIRA) is a novel method for measuring IGF-I bioactivity in human serum. We speculated that determination of IGF-I bioactivity might broaden our und...

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Bibliographic Details
Main Authors: Brugts, Michael P., van Duijn, Cornelia M., Hofland, Leo J., Witteman, Jacqueline C., Lamberts, Steven W.J., Janssen, Joseph A.M.J.L.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2010
Subjects:
Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809963/
https://ncbi.nlm.nih.gov/pubmed/20103714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0583
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