Circulating insulin-like growth factors may contribute substantially to insulin receptor isoform A and insulin receptor isoform B signalling

BACKGROUND: Only a fraction of circulating insulin-like activity is due to insulin itself. The aim of this study was to determine total serum insulin-like activity mediated via the insulin receptor isoform A (IR-A) and isoform B (IR-B) by using kinase receptor activation (KIRA) assays specific for t...

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Publicat a:Mol Cell Endocrinol
Autors principals: Varewijck, Aimee J., Brugts, Michael P., Frystyk, Jan, Goudzwaard, Jeannette A., Uitterlinden, Pieter, Waaijers, Adriana M., Feng, Yang, Dimitrov, Dimiter S., Lamberts, Steven W.J., Hofland, Leo J., Janssen, Joseph A.M.J.L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959542/
https://ncbi.nlm.nih.gov/pubmed/22982059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.08.021
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