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In active acromegaly, IGF1 bioactivity is related to soluble Klotho levels and quality of life
The value of measuring IGF1 bioactivity in active acromegaly is unknown. Soluble Klotho (S-Klotho) level is elevated in active acromegaly and it has been suggested that S-Klotho can inhibit activation of the IGF1 receptor (IGF1R). A cross-sectional study was carried out in 15 patients with active ac...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Bioscientifica Ltd
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001616/ https://ncbi.nlm.nih.gov/pubmed/24692508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-14-0028 |
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