In active acromegaly, IGF1 bioactivity is related to soluble Klotho levels and quality of life

The value of measuring IGF1 bioactivity in active acromegaly is unknown. Soluble Klotho (S-Klotho) level is elevated in active acromegaly and it has been suggested that S-Klotho can inhibit activation of the IGF1 receptor (IGF1R). A cross-sectional study was carried out in 15 patients with active ac...

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Main Authors: Varewijck, A J, van der Lely, A J, Neggers, S J C M M, Lamberts, S W J, Hofland, L J, Janssen, J A M J L
格式: Artigo
語言:Inglês
出版: Bioscientifica Ltd 2014
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001616/
https://ncbi.nlm.nih.gov/pubmed/24692508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-14-0028
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