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IGF-IR Targeted Therapy: Past, Present and Future
The IGF-I receptor (IGF-IR) has been studied as an anti-cancer target. However, monotherapy trials with IGF-IR targeted antibodies or with IGF-IR specific tyrosine kinase inhibitors have, overall, been very disappointing in the clinical setting. This review discusses potential reasons why IGF-I R ta...
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| Publicado no: | Front Endocrinol (Lausanne) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4275034/ https://ncbi.nlm.nih.gov/pubmed/25566194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00224 |
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