Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians’ offspring

The role of epigenetics in the modulation of longevity has not been studied in humans. To this aim, (1) we evaluated the DNA methylation from peripheral leukocytes of 21 female centenarians, their 21 female offspring, 21 offspring of both non-long-lived parents, and 21 young women through ELISA assa...

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Main Authors: Gentilini, Davide, Mari, Daniela, Castaldi, Davide, Remondini, Daniel, Ogliari, Giulia, Ostan, Rita, Bucci, Laura, Sirchia, Silvia M., Tabano, Silvia, Cavagnini, Francesco, Monti, Daniela, Franceschi, Claudio, Di Blasio, Anna Maria, Vitale, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776126/
https://ncbi.nlm.nih.gov/pubmed/22923132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9463-1
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