Future treatment strategies of aggressive pituitary tumors

Por Lamberts, Steven W. J., Hofland, Leo J.
Publicado em 2008

Macrophage-fibroblast interplay: a target for neuropeptide-based treatment of fibrotic disease?

Por Virakul, Sita, Dik, Willem A, Hofland, Leo J, van Hagen, P Martin, Dalm, Virgil ASH
Publicado em 2012

Influence of type-I Interferon receptor expression level on the response to type-I Interferons in human pancreatic cancer cells

Por Booy, Stephanie, van Eijck, Casper H J, Dogan, Fadime, van Koetsveld, Peter M, Hofland, Leo J
Publicado em 2014

IFN-β is a potent inhibitor of insulin and insulin like growth factor stimulated proliferation and migration in human pancreatic cancer cells

Por Booy, Stephanie, van Eijck, Casper HJ, Janssen, Joseph AMJL, Dogan, Fadime, van Koetsveld, Peter M, Hofland, Leo J
Publicado no Am J Cancer Res (2015)

Potency of Full- Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Equimolar Concentrations

Por Janssen, Joseph A. M. J. L., Hofland, Leo J., Strasburger, Christian J., van den Dungen, Elisabeth S. R., Thevis, Mario
Publicado no PLoS One (2016)

IGF-I Bioactivity in an Elderly Population: Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome

Por Brugts, Michael P., van Duijn, Cornelia M., Hofland, Leo J., Witteman, Jacqueline C., Lamberts, Steven W.J., Janssen, Joseph A.M.J.L.
Publicado em 2010

The Influence of Reactive Oxygen Species on the Adhesion of Pancreatic Carcinoma Cells to the Peritoneum

Por ten Raa, Sander, van Grevenstein, Helma MU, ten Kate, Miranda, Mangundap, Kristin M, Hofland, Leo J, Jeekel, Hans, Sluiter, Wim, van Eijck, Casper HJ
Publicado em 2007

Variations in DNA methylation of interferon gamma and programmed death 1 in allograft rejection after kidney transplantation

Por Boer, Karin, de Wit, L. Elly A., Peters, Fleur S., Hesselink, Dennis A., Hofland, Leo J., Betjes, Michiel G. H., Looman, Caspar W. N., Baan, Carla C.
Publicado no Clin Epigenetics (2016)

Does Somatostatin Have a Role in the Regulation of Cortisol Secretion in Primary Pigmented Nodular Adrenocortical Disease (PPNAD)? A Clinical and in Vitro Investigation

Por Bram, Zakariae, Xekouki, Paraskevi, Louiset, Estelle, Keil, Meg F., Avgeropoulos, Dimitrios, Giatzakis, Christoforos, Nesterova, Maria, Sinaii, Ninet, Hofland, Leo J., Cherqaoui, Rabia, Lefebvre, Hervé, Stratakis, Constantine A.
Publicado em 2014

Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors

Por Vandamme, Timon, Beyens, Matthias, de Beeck, Ken Op, Dogan, Fadime, van Koetsveld, Peter M, Pauwels, Patrick, Mortier, Geert, Vangestel, Christel, de Herder, Wouter, Van Camp, Guy, Peeters, Marc, Hofland, Leo J
Publicado no Br J Cancer (2016)

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma

Por Pivonello, Claudia, Negri, Mariarosaria, De Martino, Maria Cristina, Napolitano, Maria, de Angelis, Cristina, Provvisiero, Donatella Paola, Cuomo, Gaia, Auriemma, Renata Simona, Simeoli, Chiara, Izzo, Francesco, Colao, Annamaria, Hofland, Leo J., Pivonello, Rosario
Publicado no Oncotarget (2016)

Inhibin Alpha-Subunit (INHA) Expression in Adrenocortical Cancer Is Linked to Genetic and Epigenetic INHA Promoter Variation

Por Hofland, Johannes, Steenbergen, Jacobie, Voorsluijs, Jacoba M., Verbiest, Michael M. P. J., de Krijger, Ronald R., Hofland, Leo J., de Herder, Wouter W., Uitterlinden, Andre G., Feelders, Richard A., de Jong, Frank H.
Publicado em 2014

Regulation of steroidogenesis in a primary pigmented nodular adrenocortical disease-associated adenoma leading to virilization and subclinical Cushing’s syndrome

Por Hofland, Johannes, de Herder, Wouter W, Derks, Lieke, Hofland, Leo J, van Koetsveld, Peter M, de Krijger, Ronald R, van Nederveen, Francien H, Horvath, Anelia, Stratakis, Constantine A, de Jong, Frank H, Feelders, Richard A
Publicado em 2012

Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

Por Vitale, Giovanni, Brugts, Michael P, Ogliari, Giulia, Castaldi, Davide, Fatti, Letizia M., Varewijck, Aimee J., Lamberts, Steven W., Monti, Daniela, Bucci, Laura, Cevenini, Elisa, Cavagnini, Francesco, Franceschi, Claudio, Hofland, Leo J, Mari, Daniela, Janssen, Joseph A.M.J.L.
Publicado em 2012

Type I Interferons in the Treatment of Pancreatic Cancer: Mechanisms of Action and Role of Related Receptors

Por Vitale, Giovanni, van Eijck, Casper H. J., van Koetsveld Ing, Peter M., Erdmann, Joris I., Speel, Ernst Jan M., van der Wansem Ing, Katy, Mooij, Diana M., Colao, Annamaria, Lombardi, Gaetano, Croze, Ed, Lamberts, Steven W. J., Hofland, Leo J.
Publicado em 2007

ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a...

Por Hofland, Johannes, Hofland, Leo J, van Koetsveld, Peter M, Steenbergen, Jacobie, de Herder, Wouter W, van Eijck, Casper H, de Krijger, Ronald R, van Nederveen, Francien H, van Aken, Maarten O, de Groot, Johannes W, Links, Thera P, de Jong, Frank H, Feelders, Richard A
Publicado em 2013

Somatostatin Analogues for Receptor Targeted Photodynamic Therapy

Por Kaščáková, Slávka, Hofland, Leo J., De Bruijn, Henriette S., Ye, Yunpeng, Achilefu, Samuel, van der Wansem, Katy, van der Ploeg-van den Heuvel, Angelique, van Koetsveld, Peter M., Brugts, Michael P., van der Lelij, Aart-Jan, Sterenborg, Henricus J. C. M., ten Hagen, Timo L. M., Robinson, Dominic J., van Hagen, Martin P.
Publicado em 2014