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ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase

BACKGROUND: Adrenal Cushing’s syndrome caused by ACTH-independent macronodular adrenocortical hyperplasia (AIMAH) can be accompanied by aberrant responses to hormonal stimuli. We investigated the prevalence of adrenocortical reactions to these stimuli in a large cohort of AIMAH patients, both in viv...

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Detalhes bibliográficos
Main Authors: Hofland, Johannes, Hofland, Leo J, van Koetsveld, Peter M, Steenbergen, Jacobie, de Herder, Wouter W, van Eijck, Casper H, de Krijger, Ronald R, van Nederveen, Francien H, van Aken, Maarten O, de Groot, Johannes W, Links, Thera P, de Jong, Frank H, Feelders, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847204/
https://ncbi.nlm.nih.gov/pubmed/24034279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-142
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