Inhibition of Human Adrenocortical Cancer Cell Growth by Temozolomide in Vitro and the Role of the MGMT Gene

CONTEXT: Treatment of patients with adrenocortical carcinomas (ACC) with mitotane and/or chemotherapy is often associated with toxicity and poor tumor response. New therapeutic options are urgently needed. OBJECTIVE: The objectives of the study were to evaluate the therapeutic possibilities of temoz...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Creemers, S. G., van Koetsveld, P. M., van den Dungen, E. S. R., Korpershoek, E., van Kemenade, F. J., Franssen, G. J. H., de Herder, W. W., Feelders, R. A., Hofland, L. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155680/
https://ncbi.nlm.nih.gov/pubmed/27603910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-2768
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