ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase

BACKGROUND: Adrenal Cushing’s syndrome caused by ACTH-independent macronodular adrenocortical hyperplasia (AIMAH) can be accompanied by aberrant responses to hormonal stimuli. We investigated the prevalence of adrenocortical reactions to these stimuli in a large cohort of AIMAH patients, both in viv...

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Hlavní autoři: Hofland, Johannes, Hofland, Leo J, van Koetsveld, Peter M, Steenbergen, Jacobie, de Herder, Wouter W, van Eijck, Casper H, de Krijger, Ronald R, van Nederveen, Francien H, van Aken, Maarten O, de Groot, Johannes W, Links, Thera P, de Jong, Frank H, Feelders, Richard A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847204/
https://ncbi.nlm.nih.gov/pubmed/24034279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-142
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