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Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling

The eight metabotropic glutamate receptors (mGluRs) are key modulators of synaptic transmission and are considered promising targets for the treatment of various brain disorders. Whereas glutamate acts at a large extracellular domain, allosteric modulators have been identified that bind to the seven...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: El Moustaine, Driss, Granier, Sébastien, Doumazane, Etienne, Scholler, Pauline, Rahmeh, Rita, Bron, Patrick, Mouillac, Bernard, Banères, Jean-Louis, Rondard, Philippe, Pin, Jean-Philippe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479612/
https://ncbi.nlm.nih.gov/pubmed/22988116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205838109
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