Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. Here, we set up two assays to spe...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Moreno Delgado, David, Møller, Thor C, Ster, Jeanne, Giraldo, Jesús, Maurel, Damien, Rovira, Xavier, Scholler, Pauline, Zwier, Jurriaan M, Perroy, Julie, Durroux, Thierry, Trinquet, Eric, Prezeau, Laurent, Rondard, Philippe, Pin, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540479/
https://ncbi.nlm.nih.gov/pubmed/28661401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25233
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