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(S)-homoquisqualate: a potent agonist at the glutamate metabotropic receptor.

The synthetic quisqualate analogue, (S)-homoquisqualate was examined for activity at the glutamate metabotropic receptor, in relation to its ability to stimulate phosphoinositide hydrolysis in rat pup cerebro-cortical slices. The compound produced a robust increase in hydrolysis (EC50 = 50.2 +/- 1.6...

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Detalhes bibliográficos
Main Authors: Porter, R. H., Roberts, P. J., Jane, D. E., Watkins, J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907545/
https://ncbi.nlm.nih.gov/pubmed/1324071
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