Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.

1. We investigated the agonist and antagonist activities of 22 new phenylglycine and phenylalanine derivatives for metabotropic glutamate receptors (mGluRs) by examining their effects on the signal transduction of mGluR1, mGluR2 and mGluR6 subtypes expressed in Chinese hamster ovary cells. This anal...

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Autori principali: Sekiyama, N., Hayashi, Y., Nakanishi, S., Jane, D. E., Tse, H. W., Birse, E. F., Watkins, J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909443/
https://ncbi.nlm.nih.gov/pubmed/8730745
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