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Metabotropic Glutamate Receptor Subtype 5 Antagonists MPEP and MTEP
Glutamate regulates the function of central nervous system (CNS), in part, through the cAMP and/or IP3/DAG second messenger‐associated metabotropic glutamate receptors (mGluRs). The mGluR5 antagonist 2‐methyl‐6‐(phenylethynyl)‐pyridine (MPEP) has been extensively used to elucidate potential physiolo...
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| Publicado en: | CNS Drug Rev |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Publishing Inc
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494124/ https://ncbi.nlm.nih.gov/pubmed/16958988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00149.x |
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