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Metabotropic Glutamate Receptor Subtype 5 Antagonists MPEP and MTEP

Glutamate regulates the function of central nervous system (CNS), in part, through the cAMP and/or IP3/DAG second messenger‐associated metabotropic glutamate receptors (mGluRs). The mGluR5 antagonist 2‐methyl‐6‐(phenylethynyl)‐pyridine (MPEP) has been extensively used to elucidate potential physiolo...

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Bibliografiske detaljer
Udgivet i:CNS Drug Rev
Main Authors: Lea, Paul M., Faden, Alan I.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Inc 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494124/
https://ncbi.nlm.nih.gov/pubmed/16958988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00149.x
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