DEC-205 is a cell surface receptor for CpG oligonucleotides

Synthetic CpG oligonucleotides (ODN) have potent immunostimulatory properties exploited in clinical vaccine trials. How CpG ODN are captured and delivered to the intracellular receptor TLR9, however, has been elusive. Here we show that DEC-205, a multilectin receptor expressed by a variety of cells,...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Lahoud, Mireille H., Ahmet, Fatma, Zhang, Jian-Guo, Meuter, Simone, Policheni, Antonia N., Kitsoulis, Susie, Lee, Chin-Nien, O’Keeffe, Meredith, Sullivan, Lucy C., Brooks, Andrew G., Berry, Richard, Rossjohn, Jamie, Mintern, Justine D., Vega-Ramos, Javier, Villadangos, Jose A., Nicola, Nicos A., Nussenzweig, Michel C., Stacey, Katryn J., Shortman, Ken, Heath, William R., Caminschi, Irina
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2012
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479608/
https://ncbi.nlm.nih.gov/pubmed/22988114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208796109
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla