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DEC-205 is a cell surface receptor for CpG oligonucleotides
Synthetic CpG oligonucleotides (ODN) have potent immunostimulatory properties exploited in clinical vaccine trials. How CpG ODN are captured and delivered to the intracellular receptor TLR9, however, has been elusive. Here we show that DEC-205, a multilectin receptor expressed by a variety of cells,...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479608/ https://ncbi.nlm.nih.gov/pubmed/22988114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208796109 |
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