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DEC-205 is a cell surface receptor for CpG oligonucleotides

We have recently demonstrated that synthetic CpG oligonucleotides (ODNs), which function as potent immunostimulators, bind to the multi-lectin receptor DEC-205, resulting in their internalization. DEC-205-deficient mice exhibit impaired dendritic-cell and B-cell maturation, impaired cytokine respons...

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Autors principals: Caminschi, Irina, Meuter, Simone, Heath, William R.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661149/
https://ncbi.nlm.nih.gov/pubmed/23802064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23128
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