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DEC-205 is a cell surface receptor for CpG oligonucleotides
We have recently demonstrated that synthetic CpG oligonucleotides (ODNs), which function as potent immunostimulators, bind to the multi-lectin receptor DEC-205, resulting in their internalization. DEC-205-deficient mice exhibit impaired dendritic-cell and B-cell maturation, impaired cytokine respons...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661149/ https://ncbi.nlm.nih.gov/pubmed/23802064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23128 |
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