Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

We previously reported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective properties in newborn neural precursor cells of the dentate gyrus. Here, we provide evidence that P7C3 also protects mature neurons in brain regions outside of the hippocampus. P7C3 blocks...

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Bibliografiske detaljer
Main Authors: De Jesús-Cortés, Héctor, Xu, Pin, Drawbridge, Jordan, Estill, Sandi Jo, Huntington, Paula, Tran, Stephanie, Britt, Jeremiah, Tesla, Rachel, Morlock, Lorraine, Naidoo, Jacinth, Melito, Lisa M., Wang, Gelin, Williams, Noelle S., Ready, Joseph M., McKnight, Steven L., Pieper, Andrew A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479520/
https://ncbi.nlm.nih.gov/pubmed/23027934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213956109
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