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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

We previously reported the discovery of P7C3, an aminopropyl carbazole having proneurogenic and neuroprotective properties in newborn neural precursor cells of the dentate gyrus. Here, we provide evidence that P7C3 also protects mature neurons in brain regions outside of the hippocampus. P7C3 blocks...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: De Jesús-Cortés, Héctor, Xu, Pin, Drawbridge, Jordan, Estill, Sandi Jo, Huntington, Paula, Tran, Stephanie, Britt, Jeremiah, Tesla, Rachel, Morlock, Lorraine, Naidoo, Jacinth, Melito, Lisa M., Wang, Gelin, Williams, Noelle S., Ready, Joseph M., McKnight, Steven L., Pieper, Andrew A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479520/
https://ncbi.nlm.nih.gov/pubmed/23027934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213956109
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