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Activation of Neuronal NMDA Receptors Induces Superoxide-Mediated Oxidative Stress in Neighboring Neurons and Astrocytes

Excitotoxic neuronal death is mediated in part by NMDA receptor-induced activation of NOX2, an enzyme that produces superoxide and resultant oxidative stress. It is not known, however, whether the superoxide is generated in the intracellular space, producing oxidative stress in the neurons respondin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Reyes, Reno C., Brennan, Angela M., Shen, Yiguo, Baldwin, Ylva, Swanson, Raymond A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478885/
https://ncbi.nlm.nih.gov/pubmed/22973021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1597-12.2012
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