Tat-NR2B9c prevents excitotoxic neuronal superoxide production

The Tat-NR2B9c peptide has shown clinical efficacy as a neuroprotective agent in acute stroke. Tat-NR2B9c is designed to prevent nitric oxide (NO) production by preventing postsynaptic density protein 95 (PSD-95) binding to N-methyl-D-aspartate (NMDA) receptors and neuronal nitric oxide synthase; ho...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Chen, Yanting, Brennan-Minnella, Angela M, Sheth, Sunil, El-Benna, Jamel, Swanson, Raymond A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420863/
https://ncbi.nlm.nih.gov/pubmed/25669908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.16
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