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Superoxide and Non-ionotropic Signaling in Neuronal Excitotoxicity
Excitotoxicity is classically attributed to Ca(2+) influx through NMDA receptors (NMDAr), leading to production of nitric oxide by neuronal nitric oxide synthase and superoxide by mitochondria, which react to form highly cytotoxic peroxynitrite. More recent observations warrant revision of the class...
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| Udgivet i: | Front Neurosci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7497801/ https://ncbi.nlm.nih.gov/pubmed/33013314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00861 |
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