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Superoxide and Non-ionotropic Signaling in Neuronal Excitotoxicity
Excitotoxicity is classically attributed to Ca(2+) influx through NMDA receptors (NMDAr), leading to production of nitric oxide by neuronal nitric oxide synthase and superoxide by mitochondria, which react to form highly cytotoxic peroxynitrite. More recent observations warrant revision of the class...
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| Publié dans: | Front Neurosci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7497801/ https://ncbi.nlm.nih.gov/pubmed/33013314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00861 |
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