NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

Neuronal NMDA receptor (NMDAR) activation leads to the formation of superoxide, which normally acts in cell signaling. With extensive NMDAR activation, the resulting superoxide production leads to neuronal death. It is widely held that NMDA-induced superoxide production originates from the mitochond...

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Detaylı Bibliyografya
Asıl Yazarlar: Brennan, Angela M, Suh, Sang Won, Won, Seok Joon, Narasimhan, Purnima, Kauppinen, Tiina M, Lee, Hokyou, Edling, Ylva, Chan, Pak H, Swanson, Raymond A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746760/
https://ncbi.nlm.nih.gov/pubmed/19503084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2334
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