NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

Neuronal NMDA receptor (NMDAR) activation leads to the formation of superoxide, which normally acts in cell signaling. With extensive NMDAR activation, the resulting superoxide production leads to neuronal death. It is widely held that NMDA-induced superoxide production originates from the mitochond...

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Detalhes bibliográficos
Main Authors: Brennan, Angela M, Suh, Sang Won, Won, Seok Joon, Narasimhan, Purnima, Kauppinen, Tiina M, Lee, Hokyou, Edling, Ylva, Chan, Pak H, Swanson, Raymond A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746760/
https://ncbi.nlm.nih.gov/pubmed/19503084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2334
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