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NADPH Oxidase-2: Linking Glucose, Acidosis, and Excitotoxicity in Stroke

Significance: Neuronal superoxide production contributes to cell death in both glutamate excitotoxicity and brain ischemia (stroke). NADPH oxidase-2 (NOX2) is the major source of neuronal superoxide production in these settings, and regulation of NOX2 activity can thereby influence outcome in stroke...

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Bibliografske podrobnosti
izdano v:Antioxid Redox Signal
Main Authors: Brennan-Minnella, Angela M., Won, Seok Joon, Swanson, Raymond A.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281853/
https://ncbi.nlm.nih.gov/pubmed/24628477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5767
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