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Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase

Hypoglycemic coma and brain injury are potential complications of insulin therapy. Certain neurons in the hippocampus and cerebral cortex are uniquely vulnerable to hypoglycemic cell death, and oxidative stress is a key event in this cell death process. Here we show that hypoglycemia-induced oxidati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suh, Sang Won, Gum, Elizabeth T., Hamby, Aaron M., Chan, Pak H., Swanson, Raymond A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838937/
https://ncbi.nlm.nih.gov/pubmed/17404617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30077
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