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Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

OBJECTIVE: Hyperglycemia has been recognized for decades to be an exacerbating factor in ischemic stroke, but the mechanism of this effect remains unresolved. Here we evaluated superoxide production by neuronal NADPH oxidase as a link between glucose metabolism and neuronal death in ischemia-reperfu...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Suh, Sang Won, Shin, Byung Seop, Ma, Hualong, Van Hoecke, Michaël, Brennan, Angela M., Yenari, Midori A., Swanson, Raymond A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304737/
https://ncbi.nlm.nih.gov/pubmed/19107988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21511
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