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[(11)C]Rhodamine-123: synthesis and biodistribution in rodents

INTRODUCTION: Rhodamine-123 is a known substrate for the efflux transporter, P-glycoprotein (P-gp). We wished to assess whether rhodamine-123 might serve as a useful substrate for developing probes for imaging efflux transporters in vivo with positron emission tomography (PET). For this purpose, we...

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Main Authors: Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Morse, Cheryl L., Anderson, Kacey, Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478417/
https://ncbi.nlm.nih.gov/pubmed/22898316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.06.013
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