Recognition of Glioma Stem Cells by Genetically Modified T Cells Targeting EGFRvIII and Development of Adoptive Cell Therapy for Glioma

Eitemau Tebyg

• Pilot trial of adoptive transfer of chimeric antigen receptor transduced T cells targeting EGFRvIII in patients with glioblastoma
  gan: Goff, Stephanie L., et al.
  Cyhoeddwyd: (2019)
• Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma.
  gan: Ayguen Sahin, et al.
  Cyhoeddwyd: (2018-01-01)
• Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma
  gan: Sahin, Ayguen, et al.
  Cyhoeddwyd: (2018)
• EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss
  gan: Sampson, John H., et al.
  Cyhoeddwyd: (2013)
• Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis
  gan: Liu, Yingmiao, et al.
  Cyhoeddwyd: (2009)