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Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Glioblastoma multiforme (GBM) is the most aggressive and deadly form of adult brain cancer. Despite of many attempts to identify potential therapies for this disease, including promising cancer immunotherapy approaches, it remains incurable. To address the need of improved persistence, expansion, an...

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Foilsithe in:PLoS One
Main Authors: Sahin, Ayguen, Sanchez, Carlos, Bullain, Szofia, Waterman, Peter, Weissleder, Ralph, Carter, Bob S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033533/
https://ncbi.nlm.nih.gov/pubmed/29975720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199414
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